The Global Mediations Lab aims to be a catalyst for the study of media texts, industries, and infrastructures at a planetary scale, focusing on in-depth, carefully contextualized studies reaching beyond the usual focus on anglophone North America and Western Europe. Drawing on Comparative Media Studies/Writing and MIT’s broader strengths in cross-disciplinary methods and systems thinking, the Global Mediations Lab fosters projects bringing a critical lens to the aesthetic, industrial, and infrastructural forces at play as media migrate around the world. Focusing not on static media objects but on the active process of mediation, we aim to map out the global media landscape in its moments of contestation and transformation. We envision the GML as the center of a collaborative community of scholars reimagining media research for a globally multipolar era, asserting the need for MIT to attend to the cultural and political impacts of media technologies as they go on to transform life across the planet.